The NutriSearch Comparative Guide to Nutritional Supplements (4th edition) is an educational and consumer-based compendium that reviews and compares over 1600 nutritional products available in the United States and Canada. The guide was designed with three principal goals: to educate the consumer on the nutritional basis of disease prevention, highlighting the importance of supplementation as a vital component of a holistic approach to wellness; to provide an evidence-based approach to supplementation, focusing on the science behind the use of natural health products; and to evaluate the hundreds of nutritional products in the North American marketplace, providing guidance to the consumer on relative product value.